Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Methotrexate United States Pharmacopeia (USP) Reference Standard | 59-05-2 | MFCD00064370 | 500MG
Methotrexate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 454.44 | 59-05-2 | MFCD00064370 | 500MG
Apexbio Technology LLC Fluticasone propionate 80474-14-2 50mg
Fluticasone propionate is a synthetic glucocorticoid receptor (GR) agonist with high receptor selectivity and affinity It exerts anti-inflammatory and immunosuppressive actions by interacting with intracellular GR thereby influencing gene expression pathways and downstream cytokine responses This compound has been widely utilized in biomedical research to study inflammatory signaling mechanisms glucocorticoid receptor mediated transcriptional regulation and immune responses associated with asthma allergic rhinitis and related inflammatory diseases Reported in vitro studies demonstrate fluticasone propionate s GR agonist activity with an IC50 value in the subnanomolar range (approximately 0 5 nM) supporting its frequent utilization as a standard GR agonist in receptor-binding assays and inflammation-related experiments
Apexbio Technology LLC Flavopiridol hydrochloride 131740-09-5 10mM (in 1mL DMSO)
Flavopiridol hydrochloride is a selective inhibitor of cyclin-dependent kinases (CDKs) specifically targeting CDK1 CDK2 CDK4 and CDK6 with reported IC50 values approximately 41 nM and CDK7 with an IC50 of about 300 nM Additionally it has been observed to inhibit EGFR and protein kinase A at micromolar concentrations By inhibiting CDK activity flavopiridol hydrochloride disrupts cell cycle progression inducing G1 phase arrest as demonstrated in breast cancer cell lines Furthermore its capacity to inhibit phosphorylation of Rb protein and suppress anti-apoptotic proteins such as Mcl-1 and XIAP facilitates apoptosis in lymphoma cell models Flavopiridol hydrochloride is utilized in preclinical studies of cell cycle regulation apoptosis signaling and cancer research including experiments using xenograft tumor models in mice
Sigma Aldrich Fine Chemicals Biosciences Alfuzosin for system suitability A European Pharmacopoeia (EP) Reference Standard | 81403-68-1 | MFCD00879135 |
Alfuzosin for system suitability A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 425.91 | 81403-68-1 | MFCD00879135 |
Sigma Aldrich Fine Chemicals Biosciences Nateglinide impurity B European Pharmacopoeia (EP) Reference Standard | 105816-05-5 |
Nateglinide impurity B European Pharmacopoeia (EP) Reference Standard | Mol Wt: 317.42 | 105816-05-5 |
Sigma Aldrich Fine Chemicals Biosciences Glyburide Related Compound B United States Pharmacopeia (USP) Reference Standard | 21165-77-5 | 25MG
Glyburide Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 426.87 | 21165-77-5 | 25MG
Sigma Aldrich Fine Chemicals Biosciences 5-Amino-2,4,6-triiodo-N-methylisophthalamic acid United States Pharmacopeia (USP) Reference Standard | 2280-89-9 | 50MG
5-Amino-2,4,6-triiodo-N-methylisophthalamic acid United States Pharmacopeia (USP) Reference Standard | Mol Wt: 571.88 | 2280-89-9 | 50MG
Medchemexpress LLC Butyl 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoate | 32643-00-8 | MFCD09838330 | 25mg
Bumetanide impurity 2 is an impurity of Bumetanide (HY-17468)
Cayman Chemical DIpyrIdamole 10g
A PDE5A inhibitor (IC50 = 574 nM) that prevents platelet aggregation by increasing cGMP levels and blocking the reuptake of adenosine via red blood cells; scavenges the free radicals that inactivate COX, leading to the inhibition of platelet activation and thrombin generation; also inhibits PDE11A (IC50 = 370 nM) and ENT1 (Ki = 8.18 nM); inhibits replication of SARS-CoV-2 in Vero E6 cells at 100 nM
Selleck Chemical LLC Plerixafor (AMD3100) 10mg 110078-46-1 JM 3100
Plerixafor (AMD3100, JM 3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Sulfamerazine (Standard) | 127-79-7 | 99.7% | 25 MG
Sulfamerazine (Standard) is the analytical standard for Sulfamerazine. It is intended for research and analytical applications, serving as a reference standard for assays.
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
Medchemexpress LLC Ramipril (HOE-498) | 87333-19-5 | 99.4% | 1 ML
Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 nM. It enhances the activity of ACE-associated CK2 and the phosphorylation of ACE Ser1270 in cultured endothelial cells. Chronic in vivo administration to rats significantly reduces LPS-induced apoptosis. It inhibits systolic blood pressure (SBP) with an IC50 of 1.97 mg/kg in spontaneously hypertensive rats (SHR).
- Potent angiotensin-converting enzyme (ACE) inhibitor
- Enhances ACE-associated CK2 activity
- Reduces LPS-induced apoptosis in rats
- Inhibits systolic blood pressure (SBP)
- For research use only
Chemscene ChemScene | Methylliberine | 5G | CS-0133882 | 0.98 | 51168-26-4| | 224.22
ChemScene | Methylliberine | 5G | CS-0133882 | 0.98 | 51168-26-4| | 224.22
Sigma Aldrich Fine Chemicals Biosciences Tranexamic acid impurity D
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Cayman Chemical D-a-Tocopheryl QuInon 250mg
An oxidative metabolite of vitamin E; has antioxidant activity in ORAC and radical trapping assays at 25 µM; inhibits (1S,3R)-RSL3-induced ferroptosis in Q7 cells (EC50 = 0.233 µM); decreases serum MDA and blood glucose levels and restores the number and diversity of intestinal microflora in a rat model of high cholesterol and cholate diet-induced NASH at 20 mg/kg